hrp0092p1-61 | Fat, Metabolism and Obesity | ESPE2019

Association Among PGRN, HMGB1, and Obesity Related Markers in Young Rat Model of High Fat Diet-Induced Obesity

Chen Hongshan , Li Dan , Zhang Yuanyuan , Huang Siqi , He Xiaohua

Objective: We aim to investigate the association among progranulin (PGRN), high-mobility group box 1 (HMGB1), and obesity related markers in young rat model of high fat diet-induced obesity.Materials and Methods: 20 Male Sprague-Dawley (SD) rats at the age of 21 days were divided into two groups randomly. The rats were fed with normal diet (NC group) or high-fat diet (OB group). The NC group and OB group were sacrificed ...